Thesis for the degree of Doctor of Medicine REWARD-RELATED GENES AND ALCOHOL DEPENDENCE
نویسندگان
چکیده
REWARD-RELATED GENES AND ALCOHOL DEPENDENCE
منابع مشابه
Alcoholism – the Worst Addiction
Introduction: The most common substance of abuse/dependence in patients presenting for treatment in western countries is alcohol. Ethyl alcohol or ethanol which is also called medicinal alcohol is used as an official drug compendium. It is also administered as an antidote in methanol poisoning. However, regular consumption of high amounts of alcoholic drinks induces dependence and addiction lea...
متن کاملMolecular Genetics of Alcohol Dependence and Related Endophenotypes
Alcohol dependence is a worldwide public health problem, and involves both environmental and genetic vulnerability factors. The heritability of alcohol dependence is rather high, ranging between 50% and 60%, although alcohol dependence is a polygenic, complex disorder.Genome-wide scans on large cohorts of multiplex families, including the collaborative study on genetics of alcoholism (COGA), em...
متن کامل[Alcohol dependence and polymorphisms of serotonin-related genes].
Genetic factors have a non-specific but significant impact on the risk of alcohol-dependence. Molecular genetic analyses are now less devoted to the genes involved in the metabolism of ethanol, focusing on core concepts of addiction, such as arousal, pleasure, reward, craving, and impulsivity. Indeed, the neuro-cognitive functions, temperament traits and psycho-behavioral specificities of patie...
متن کاملAlcohol dependence and gene x environment interaction in emotion regulation: Is serotonin the link?
Alcohol dependence is characterized by frequent, compulsive and uncontrolled consumption of alcohol associated with behavior of maladaption and destruction. It is an etiologically and clinically heterogeneous syndrome, moderately to highly heritable, and caused by interaction of genes and environment. Alcohol dependence is related to other psychiatric diseases by common neurobiological pathways...
متن کاملThe genetic components of alcohol and nicotine co-addiction: from genes to behavior.
Co-occurrence of alcohol and nicotine addiction in humans is well documented and there is good evidence that common genes may contribute to both disorders. Although genetic factors contributing to tobacco and alcohol problem use have been well established through adoption, twin and family studies, specific genes remain to be identified and their mode of action elucidated. Recent work from human...
متن کامل